Categories

lab

Comparing Multisert and AutonoMe.

Comparing Multisert and AutonoMe IOL injectors, a study found both allowed safe implantation, but Multisert showed more consistent behavior and less injector damage.

In lab, news, Sep 26, 2023

Introducing Dynamic Stimulation Aberrometry

Researchers introduced dynamic stimulation aberrometry (DSA) to objectively measure binocular accommodation in 91 patients, finding that accommodative amplitude decreases with age and that DSA records pupil motility dynamically.

In lab, news, , Apr 29, 2023

Recommending realistic incision sizes!

A recent study analyzed the recommended incision sizes of 13 intraocular lens injector systems in cataract surgery, finding that manufacturers' recommendations often lead to intraoperative incision enlargement, and in some cases, require larger incisions than recommended.

In lab, news, Feb 16, 2023

We're Recruiting!

The David J Apple Center for Vision Research is recruiting a student researcher to work on new projects involving material science applications for posterior segment ocular disease. The position involves laboratory bench research, rheological analyses, and Wet Lab surgery projects, with the possibility to conduct a medical doctoral thesis.

In lab, news, Jan 23, 2023

Prize-winning AAO 2022

Dr. Gerd Auffarth receives the AAO Life Achievement Honor Award in Chicago, marking 30 years since his first attendance. He is also recognized for his video "CSI Heidelberg - A view from Inside," which won the Grand Prize of the AAO Global Video Contest.

In lab, news, Sep 29, 2022

Il gruppo 22 di Milano

Group photo in Milan

In lab, news, Sep 18, 2022

Merci beaucoup Philippe

Professor Philippe Sourdille delivered the 1st David J. Apple MD Memorial Lecture, "Events I Have Witnessed Over Many Years," at the University-Eye-Clinic in Heidelberg, Germany, sharing a fascinating journey through decades of ophthalmic research and technology.

In lab, news, Jul 18, 2022

Silicone oil drug delivery

"Intravitreal Application: Physicochemical Properties of Drugs Dissolved in Silicone Oils of Different Density in Comparison to the Porcine Vitreous Body" by Hammer et al. (2022) investigates the distribution of anti-infective drugs in silicone oil-filled eyes compared to natural porcine vitreous bodies. The study finds that silicone oil, especially heavier-than-water silicone oil, can be used as a drug reservoir, and that protein binding in the vitreous body occurs with hydrophilic drugs like vancomycin.

In lab, news, Jul 12, 2022

Breaking news from Seoul

The David J Apple Laboratory won a prize at the APACRS Film Festival for "CSI Heidelberg: A view from inside," a video showcasing the laboratory's work in a CSI-style format.

In lab, news, Jun 11, 2022

Announcement: Prof. Auffarth to present the 2022 Ernst Bodenheimer Memorial Lecture.

Prof. Gerd U. Auffarth, MD, PhD, delivered the 2022 Ernst Bodenheimer Memorial Lecture on "Corneal Treatments and Surgery 2022: What We are Doing Differently" at the Wilmer Eye Institute, Johns Hopkins University.

In lab, news, Apr 27, 2022

Physico-chemical parameters of Silicone Oil

The study examined the effects of biological media on silicone oil used as an intraocular tamponade in retinal detachment surgery. It found that prolonged exposure to the eye does not alter the oil's physicochemical parameters, but the addition of high-molecular-weight components may decrease emulsion stability.

In lab, news, Feb 06, 2022

Pupil dynamics

This study compares pupil size after three different strategies for intraocular lens (IOL) fixation: anterior iris-fixation, retropupillary iris-fixation, and in-the-bag implantation. The results show that all three strategies do not impair pupil constriction in normal light conditions, but retropupillary iris-fixation results in smaller scotopic pupil sizes compared to the other two methods.

In publication, lab, Nov 26, 2021

The Nuc'Cracker

ESCRS offers educational resources, including the "ESCRS 100" video series, live streaming of cataract surgery, and the ESCRS IOL Calculator.

In lab, news, Oct 10, 2021

The 80th anniversary of David Apple

David J. Apple was a renowned ophthalmic pathologist who made significant contributions to the field of intraocular lens (IOL) research and ophthalmic surgery. He was a medical historian and biographer of Sir Harold Ridley, the inventor of the IOL. Apple founded the Center for Developing World Ophthalmology and was a pioneer in IOL research, improving the world that Ridley's invention had changed. He received numerous honors and awards for his work, including the Life Achievement Honor Award and the ASCRS Innovator's Award.

In lab, history, Sep 14, 2021

Singapore winner!

CSI Heidelberg Episode 4: DMEK with EndoArt, a prize-winning video, showcases the innovative EndoArt artificial implant used in place of human donor tissue for Descemet membrane endothelial keratoplasty (DMEK).

In lab, news, Aug 01, 2021

Comparing preloaded IOL-injector systems

The study compared a new intraocular lens (IOL) injector system, multiSert, against three standard injector systems in porcine eyes. The results showed that multiSert achieved better results in incision enlargement, ease of use, delivery time, and performance when used with the appropriate incision size and implantation method.

In lab, news, Jun 15, 2021

Corneal Centre to Periphery: Astigmatism Changes

The study analyzed corneal topography data from 641 elderly patients to assess mid-peripheral astigmatism. It found that central corneal astigmatism differs from mid-peripheral measurements, with a greater difference in patients with against-the-rule, oblique, and high astigmatism. The magnitude of astigmatism decreases with distance from the center, but the axis remains largely unchanged.

In lab, news, Apr 08, 2021

Using ANTERION® to assess IOL opacification.

Researchers used high-resolution optical coherence tomography to study the correlation between localized calcification on intraocular lenses and straylight, finding a significant link between the two.

In lab, news, Mar 29, 2021

Supplementary IOL calcification

Researchers analyzed explanted intraocular lenses from polypseudophakic eyes with supplementary sulcus-supported lenses, finding calcification in both capsular bag and supplementary lenses, with varying morphology and patterns related to environmental factors and comorbidities.

In lab, research, Jul 27, 2020

Prizewinning work on Infra-red vision

The Rupp+Hubrach Science Prize 2020 was awarded to Asu Rayamajhi for their Master's thesis on measuring infrared-light visibility thresholds in diabetic and healthy patients using a two-photon ophthalmoscope.

In lab, news, Jun 22, 2020

Chinese presentation

The text discusses David J. Apple's laboratory experience and how ophthalmologists can contribute to the innovative development of artificial crystalline lenses. It includes a link to a presentation by Prof. Auffarth, which is in English, and thanks Eyebright for compiling and translating the content.

In lab, news, Jun 21, 2020

Powerlist2020: Auffarth

"The Ophthalmologist" magazine published a "Ranking" of the "100 most influential personalities in ophthalmology worldwide" This list is updated every two years, since 2014, and once again, Prof Gerd Auffarth is listed. The ranking includes not just eye surgeons but the research scientists and engineers as well as industry leaders.

In lab, news, Apr 06, 2020

Eradicating PCO

Gerd Auffarth celebrates David Apple's landmark paper on eradicating posterior capsule opacification, highlighting its significance in reducing YAG laser procedures and improving cataract surgery techniques.

In lab, news, Mar 29, 2020

Welcome 2020: New website

The David J Apple Lab celebrates the new year with a revamped website featuring contributor-based content on IOL research and history. They look forward to the ESCRS Congress in Amsterdam and reflect on their successful 2019, marked by publications in peer-reviewed journals on IOL studies.

In lab, news, Jan 01, 2020

70th IOL anniversary

"Today marks the 70th anniversary of Sir Harold Ridley's groundbreaking implantation of the first intraocular lens (IOL) at St. Thomas's Hospital in London on November 29, 1949."

In history, lab, Nov 29, 2019

Steinbeis Center

The David J Apple Center for Vision Research is a Steinbeis Research Center focused on intraocular devices, with research and clinical work managed within the center.

In lab, news, Mar 01, 2016

(Archive) Welcome Patrick

Dr. Patrick Merz, a research biotechnologist with six years of experience, joins the David J Apple International Laboratory for Ocular Pathology as Laboratory Leader, overseeing research programs and managing facilities.

In lab, news, May 01, 2015

Welcome

The David J Apple Laboratory continues the pioneering work of Dr. David Apple which focuses on intraocular lens research and improving cataract surgery techniques.

In lab, Jan 07, 2013

Why Heidelberg?

Heidelberg University is a public research university in Germany, founded in 1386. It is known for its strong research tradition, with 55 Nobel Prize winners affiliated with the university. The university has two main campuses, one in the Old Town and another in Neuenheimer Feld, which houses the medical and natural sciences faculties. Heidelberg is consistently ranked among Europe's top universities, with a strong focus on international education and research collaborations.

In history, lab, Oct 24, 2012

Moving to Heidelberg.

“For us, it is a great honour to be able to carry on the legacy of this great man,” says the CEO of the company. “We are proud to be part of the project,’ he adds, “and we are looking forward to working with the team.”

In lab, news, Sep 11, 2012

news

Appeal for Nepal

Today marks the 70th anniversary of Sir Harold Ridley’s pioneering intraocular lens (IOL) operation, performed at St Thomas’s Hospital in London on November 29, 1949.

In news, Nov 29, 2023

Comparing Multisert and AutonoMe.

Comparing Multisert and AutonoMe IOL injectors, a study found both allowed safe implantation, but Multisert showed more consistent behavior and less injector damage.

In lab, news, Sep 26, 2023

Overcoming implantation challenges with SING IMT

The SING IMT is a second-generation implantable miniature telescope designed to improve visual acuity and quality of life in patients with late-stage age-related macular degeneration (AMD). It features a smaller incision and improved surgical techniques compared to its predecessor. The device has shown significant improvements in distance and near visual acuity and is considered safe and effective in short-term studies.

In news, Aug 01, 2023

Introducing Dynamic Stimulation Aberrometry

Researchers introduced dynamic stimulation aberrometry (DSA) to objectively measure binocular accommodation in 91 patients, finding that accommodative amplitude decreases with age and that DSA records pupil motility dynamically.

In lab, news, , Apr 29, 2023

Two Apple cores

Dr. David J. Apple, a renowned ophthalmologist and pathologist, founded the David J. Apple Laboratory for Ophthalmic Devices Research. He trained over 200 students and doctors, known as the "Apple Korps," and made significant contributions to cataract surgery and intraocular lens (IOL) implantation. After his death in 2011, his laboratory was transferred to the University of Heidelberg, Germany, where Dr. Gerd U. Auffarth continues his work, now known as the Auffarth-Apple Korps.

In news, history, Mar 01, 2023

Recommending realistic incision sizes!

A recent study analyzed the recommended incision sizes of 13 intraocular lens injector systems in cataract surgery, finding that manufacturers' recommendations often lead to intraoperative incision enlargement, and in some cases, require larger incisions than recommended.

In lab, news, Feb 16, 2023

We're Recruiting!

The David J Apple Center for Vision Research is recruiting a student researcher to work on new projects involving material science applications for posterior segment ocular disease. The position involves laboratory bench research, rheological analyses, and Wet Lab surgery projects, with the possibility to conduct a medical doctoral thesis.

In lab, news, Jan 23, 2023

Nepal Appeal

"Remember 29th November 1949, the day Sir Harold Ridley implanted the first intraocular lens (IOL) at St. Thomas’s Hospital in London, marking a significant milestone in ophthalmology."

In news, Nov 29, 2022

Prize-winning AAO 2022

Dr. Gerd Auffarth receives the AAO Life Achievement Honor Award in Chicago, marking 30 years since his first attendance. He is also recognized for his video "CSI Heidelberg - A view from Inside," which won the Grand Prize of the AAO Global Video Contest.

In lab, news, Sep 29, 2022

Il gruppo 22 di Milano

Group photo in Milan

In lab, news, Sep 18, 2022

Merci beaucoup Philippe

Professor Philippe Sourdille delivered the 1st David J. Apple MD Memorial Lecture, "Events I Have Witnessed Over Many Years," at the University-Eye-Clinic in Heidelberg, Germany, sharing a fascinating journey through decades of ophthalmic research and technology.

In lab, news, Jul 18, 2022

Silicone oil drug delivery

"Intravitreal Application: Physicochemical Properties of Drugs Dissolved in Silicone Oils of Different Density in Comparison to the Porcine Vitreous Body" by Hammer et al. (2022) investigates the distribution of anti-infective drugs in silicone oil-filled eyes compared to natural porcine vitreous bodies. The study finds that silicone oil, especially heavier-than-water silicone oil, can be used as a drug reservoir, and that protein binding in the vitreous body occurs with hydrophilic drugs like vancomycin.

In lab, news, Jul 12, 2022

Platinum Performance!

The German Congress of Ophthalmic Surgeons (DOC) in Nuremberg, Germany, on June 25, 2022, was the largest face-to-face meeting in three years with 5,400 delegates. Researchers from the David J Apple Center for Vision Research in Heidelberg won four of the seven "Conference Best Paper Awards," with Prof. Dr. med. Gerd U. Auffarth receiving the first-ever Platinum Medal.

In laboratory, news, Jun 26, 2022

Breaking news from Seoul

The David J Apple Laboratory won a prize at the APACRS Film Festival for "CSI Heidelberg: A view from inside," a video showcasing the laboratory's work in a CSI-style format.

In lab, news, Jun 11, 2022

Announcement: Prof. Auffarth to present the 2022 Ernst Bodenheimer Memorial Lecture.

Prof. Gerd U. Auffarth, MD, PhD, delivered the 2022 Ernst Bodenheimer Memorial Lecture on "Corneal Treatments and Surgery 2022: What We are Doing Differently" at the Wilmer Eye Institute, Johns Hopkins University.

In lab, news, Apr 27, 2022

Physico-chemical parameters of Silicone Oil

The study examined the effects of biological media on silicone oil used as an intraocular tamponade in retinal detachment surgery. It found that prolonged exposure to the eye does not alter the oil's physicochemical parameters, but the addition of high-molecular-weight components may decrease emulsion stability.

In lab, news, Feb 06, 2022

Polyimide cannulas

Researchers compared the injection times of high-viscosity silicone oils using polyimide and metal cannulas. Polyimide cannulas significantly reduced injection times, allowing for the use of ultra-high-viscosity oils, and prewarming the oil further decreased injection times.

In research on silicone oil, news, Feb 06, 2022

In memory of Emanuel Rosen

Emanuel Rosen, a renowned ophthalmic surgeon, left a lasting impact on the field of cataract and refractive surgery. He was a unifying force, introducing key elements like ESCRS, JCRS, and EuroTimes, which continue to support global development in the field.

In news, Nov 23, 2021

Xactitude!

This study evaluates the xact Mono-EDoF ME4 IOL, a new hybrid monofocal lens with extended depth of focus, in 28 patients undergoing cataract surgery. The results show good functional outcomes for far and intermediate distance visual acuity and low levels of photic phenomena.

In clinical, news, Oct 12, 2021

The Nuc'Cracker

ESCRS offers educational resources, including the "ESCRS 100" video series, live streaming of cataract surgery, and the ESCRS IOL Calculator.

In lab, news, Oct 10, 2021

Singapore winner!

CSI Heidelberg Episode 4: DMEK with EndoArt, a prize-winning video, showcases the innovative EndoArt artificial implant used in place of human donor tissue for Descemet membrane endothelial keratoplasty (DMEK).

In lab, news, Aug 01, 2021

Comparing preloaded IOL-injector systems

The study compared a new intraocular lens (IOL) injector system, multiSert, against three standard injector systems in porcine eyes. The results showed that multiSert achieved better results in incision enlargement, ease of use, delivery time, and performance when used with the appropriate incision size and implantation method.

In lab, news, Jun 15, 2021

Corneal Centre to Periphery: Astigmatism Changes

The study analyzed corneal topography data from 641 elderly patients to assess mid-peripheral astigmatism. It found that central corneal astigmatism differs from mid-peripheral measurements, with a greater difference in patients with against-the-rule, oblique, and high astigmatism. The magnitude of astigmatism decreases with distance from the center, but the axis remains largely unchanged.

In lab, news, Apr 08, 2021

Using ANTERION® to assess IOL opacification.

Researchers used high-resolution optical coherence tomography to study the correlation between localized calcification on intraocular lenses and straylight, finding a significant link between the two.

In lab, news, Mar 29, 2021

IOL fixed to the capsulotomy!

A European multicenter trial found that a new IOL fixed to a femtosecond laser-made capsulotomy resulted in less decentration, tilt, and rotation, providing excellent visual and refractive outcomes over 12 months.

In Clinical , news, Feb 27, 2021

Reversible Trifocality

A 49-year-old woman underwent bilateral exchange of a supplementary trifocal sulcus-fixated intraocular lens to correct a residual refractive error six months after the initial duet procedure. The exchange improved her uncorrected distance visual acuity and allowed for complete spectacle independence, demonstrating the reversibility and safety of the duet procedure.

In clinical, news, Dec 01, 2020

Remember 29th November!

"Today, November 29, 2020, marks the 71st anniversary of Sir Harold Ridley's first implantation of an intraocular lens (IOL) at St Thomas's Hospital in London on November 29, 1949."

In news, history, Nov 29, 2020

CSI: Heidelberg. Episode 4 DMEK with EndoArt®

The EndoArt, an artificial endothelial replacement membrane, has shown promising results in treating chronic corneal edema. This dome-shaped, 50-μm thick implant is made of a flexible, hydrophilic acrylic material and is designed to replace the diseased endothelium. It is implanted using the "push through" technique and has been shown to significantly reduce central corneal thickness and improve visual acuity in patients. The device has several advantages over traditional donor tissue, including being off-the-shelf, non-biological, and not requiring immunosuppressive treatment.

In news, Clinical, Oct 11, 2020

4. Heidelberger Helmholtztage, 27 & 28 November

The 4th Heidelberg Helmholtz Days will take place on November 27-28, 2020, as a hybrid meeting at the Palatin Congress and Cultural Centre in Wiesloch, Heidelberg. The event will have 150 in-person attendees and offer live online lectures, with a focus on current topics related to Hermann Helmholtz's work.

In event, news, Oct 03, 2020

Pinhole Xtrafocus

Heidelberg University Eye Clinic successfully treated a patient with radial keratotomy 22 years prior using a Morcher Xtrafocus lens, correcting fluctuating residual refraction after cataract surgery.

In Clinical, news, Sep 01, 2020

The aesthetics of iris reconstruction

A study evaluated the aesthetic outcome of iris reconstruction using a custom-made artificial iris prosthesis in patients with traumatic partial or total aniridia. The results showed good aesthetic outcomes, with patients, eye doctors, and laymen rating the overall aesthetic outcome highly. Pupil centration was a key factor correlating with aesthetic satisfaction, and the artificial iris was slightly brighter than the residual iris and fellow eye iris.

In laboratory, news, Aug 18, 2020

IOL sutured to an Artificial Iris - does it affect the IOL's optics?

Researchers assessed the optical quality of monofocal intraocular lenses (IOLs) sutured to an artificial iris, finding that while the lenses' modulation transfer function (MTF) decreased slightly, the changes were clinically irrelevant.

In laboratory, news, Aug 05, 2020

Anneke Worst (1928-2020)

Ophtec, a Dutch IOL manufacturer, was founded by Jan and Anneke Worst. Anneke Worst passed away in 2020, and the company continues to innovate with products like the Precizon Go IOL.

In ophthalmology, news, Aug 04, 2020

Dry eye drops

Evaporative dry eye (EDE) is a common condition where tears evaporate too quickly, causing discomfort, irritation, and blurred vision. It is often caused by meibomian gland dysfunction, which can be treated with warm compresses, thermal pulsation, intense pulsed light, and meibomian gland probing. EDE can also be managed with topical medications like spironolactone and azithromycin.

In clinical, news, Aug 03, 2020

Prizewinning work on Infra-red vision

The Rupp+Hubrach Science Prize 2020 was awarded to Asu Rayamajhi for their Master's thesis on measuring infrared-light visibility thresholds in diabetic and healthy patients using a two-photon ophthalmoscope.

In lab, news, Jun 22, 2020

Chinese presentation

The text discusses David J. Apple's laboratory experience and how ophthalmologists can contribute to the innovative development of artificial crystalline lenses. It includes a link to a presentation by Prof. Auffarth, which is in English, and thanks Eyebright for compiling and translating the content.

In lab, news, Jun 21, 2020

After Lock-down - how to re-start?

The webinar, "SIFI Global Webinar," held on May 9, 2020, discussed the challenges of restarting cataract surgery after lockdown restrictions due to the COVID-19 pandemic. The panel, consisting of seven surgeons from Asia and Europe, covered topics such as patient interview protocols, COVID-19 testing, ocular infection, and tele-ophthalmology. The webinar aimed to provide guidance on safely resuming clinical and surgical practices.

In news, COVID 19, May 11, 2020

Powerlist2020: Auffarth

"The Ophthalmologist" magazine published a "Ranking" of the "100 most influential personalities in ophthalmology worldwide" This list is updated every two years, since 2014, and once again, Prof Gerd Auffarth is listed. The ranking includes not just eye surgeons but the research scientists and engineers as well as industry leaders.

In lab, news, Apr 06, 2020

Eradicating PCO

Gerd Auffarth celebrates David Apple's landmark paper on eradicating posterior capsule opacification, highlighting its significance in reducing YAG laser procedures and improving cataract surgery techniques.

In lab, news, Mar 29, 2020

Visualising rays in IOLs

The study visualized and analyzed the optical performance of four intraocular lens (IOL) models using a ray propagation imaging technique and modulation transfer function (MTF) measurements. The IOLs included a monofocal, bifocal, trifocal, and extended-depth-of-focus (EDOF) lens. The results showed distinct foci for distance and near vision in the bifocal and EDOF IOLs, and three distinct foci in the trifocal IOL. The technique allowed for a qualitative assessment and comparison of light energy distribution between different IOL models.

In research, news, Feb 05, 2020

EDOF IOL research

This study compares the image quality of three extended depth-of-focus (EDOF) intraocular lens models in monochromatic and polychromatic light. The results show that EDOF IOLs are more resistant to chromatic effects and provide better through-focus performance than monofocal IOLs, but differences in optical design and pupil dependency should be considered for optimal patient outcomes.

In research , news, Jan 20, 2020

Reasons for explanting IOLs

The Apple Lab research team analyzed 200 intraocular lens (IOL) explants, finding that the main reasons for explantation were IOL opacification (76.5%) and dislocation (13.5%). Most explants were hydrophilic acrylic lenses from a single manufacturer.

In research, news, Jan 18, 2020

Welcome 2020: New website

The David J Apple Lab celebrates the new year with a revamped website featuring contributor-based content on IOL research and history. They look forward to the ESCRS Congress in Amsterdam and reflect on their successful 2019, marked by publications in peer-reviewed journals on IOL studies.

In lab, news, Jan 01, 2020

Wolfgang Haigis: in memoriam

Prof. Dr. Wolfgang Haigis, a renowned physicist, passed away on October 15, 2019, at the age of 72. He was a pioneer in biometry and developed the Haigis formula, used globally for cataract surgery.

In innovator, news, Oct 18, 2019

Small-aperture IOL results.

Researchers evaluated the visual outcomes of 13 cataract patients with a small-aperture IOL in one eye and a segmental-refractive bifocal IOL in the other, showing improved binocular visual results and minimal photic phenomena.

In research, news, Sep 12, 2019

Straylight from glistenings

Glistenings in hydrophobic acrylic intraocular lenses (IOLs) are fluid-filled microvacuoles that can negatively impact visual function. Studies have shown that severe glistenings can mildly reduce contrast sensitivity and visual acuity. The formation of glistenings is highly dependent on IOL material, with hydrophobic acrylic materials being most affected. In-vitro studies have been conducted to accelerate glistening formation and evaluate the optical quality of IOLs. Results indicate that a limited number of glistenings does not significantly affect image quality, but dense glistenings can lead to small deteriorations in optical performance.

In publication, news, Jul 01, 2019

CSI:Heidelberg Episode 2

"CSI Heidelberg Episode 2 focuses on multifocal and EDOF (Extended Depth of Focus) intraocular lens (IOL) technology, highlighting their features, benefits, and challenges.

In news, publication, Oct 01, 2018

Functional results and photic phenomena with Mini WELL Ready IOL

The study evaluated the clinical outcomes of the Mini WELL Ready extended-depth-of-focus intraocular lens (EDOF-IOL) in 14 cataract patients. The lens provided good postoperative functional results at far and intermediate distances, with high rates of spectacle independence and satisfaction in everyday life. Patients reported little to no dysphotopsia, and the lens improved visual and reading acuity at reading distances.

In news, publication, Aug 28, 2018

Optical Quality July 1, 2018

New research from the David J Apple Lab reveals that pars plana vitrectomy with gas injection increases the risk of secondary calcification in hydrophilic acrylic intraocular lenses, necessitating IOL exchange.

In publication, news, Jul 01, 2018

Lab at ASCRS•ASOA ANNUAL MEETING (Washington DC)

The David J Apple Laboratory will be exhibiting at the 2018 ASCRS-ASOA Annual Meeting in Washington, DC, at booth 762.

In news, Apr 14, 2018

Hydrophilic acrylic IOLs and Lamellar keratoplasty

Researchers at the David J Apple International Laboratory for Ocular Pathology analyzed 13 hydrophilic intraocular lenses (IOLs) that became opacified after posterior lamellar keratoplasty, finding that the opacification was caused by calcium phosphate deposits on the IOL surface. This opacification significantly deteriorated the optical quality of the IOLs. The study suggests that the instillation of air or gas into the anterior chamber during these procedures increases the risk of IOL opacification, and recommends avoiding hydrophilic acrylic IOLs in patients who may require such procedures.

In news, publication, Aug 22, 2017

CSI: Heidelberg Episode 3

"CSI Heidelberg Episode 3 focuses on multifocal and extended depth-of-focus (EDOF) intraocular lens (IOL) technology, highlighting the differences and working principles of various presbyopia-correcting IOLs."

In news, publication, Aug 30, 2016

CSI:Heidelberg Episode 1

The Winner - Best Video at the annual meeting of ESCRS 2018 in Vienna. This is the first epsiode of a series about the work done in the laboratory. The first video was shot in a CSI: Crime Scene Investigation style. The video series informs the viewer how we operate.

In news, publication, Aug 30, 2016

(ARCHIVE) Welcome Lucia

Dr. Lucia Poggi, a cell biology leader, has joined the David J Apple International Laboratory for Ocular Pathology. She has a background in cellular-resolution microscopy and researches in-vivo cell biology, focusing on asymmetric cell division and fate identity acquisition during ocular development and regeneration.

In staff, news, Jul 15, 2016

(ARCHIVE) Welcome Sonja

The David J Apple International Laboratory for Ocular Pathology is a leading research center for intraocular devices, continuing the work of renowned expert David J Apple. The lab focuses on improving IOL design, materials, and implantation techniques to avoid complications.

In staff, news, Jul 01, 2016

2016 Heidelberg Helmholtz Symposium

The 2016 Heidelberg Helmholtz Symposium, hosted by the David J Apple Center for Vision Research, features workshops and presentations on contemporary ophthalmology topics, with all didactic sessions in German.

In news, Jun 29, 2016

Steinbeis Center

The David J Apple Center for Vision Research is a Steinbeis Research Center focused on intraocular devices, with research and clinical work managed within the center.

In lab, news, Mar 01, 2016

Albert Galand 1938 - 2015.

Albert Galand (1938-2015) was a pioneer in capsular IOL design and intra-capsular techniques. He developed novel capsulotomy methods, including the envelope technique, and designed lenses for capsular implantation. Galand was a strong advocate for in-the-bag fixation of IOLs and organized international meetings to promote this approach. His contributions to ophthalmology were significant, and his ideas continue to influence IOL development.

In pioneer, news, Jan 06, 2016

Seasonal greetings

The David J Apple Laboratory extends seasonal greetings, wishing clients and friends a Merry Christmas and a peaceful, prosperous, and healthy New Year. They look forward to working together in 2016.

In news, Dec 23, 2015

New Look for the Lab

Apple has expanded its use of recycled materials across its products, including 59% recycled aluminum, 45% certified recycled rare earth elements, and 30% certified recycled tin. The company aims to use only renewable or recyclable materials in its products and has made significant progress toward eliminating plastics from its packaging.

In news, Nov 02, 2015

Jan Worst 1928 to 2015

Jan Worst, a pioneer in intraocular lens (IOL) design and co-founder of Ophtec, died on September 25, 2015, in Groningen, Netherlands. He developed the iris claw lens and phakic IOLs, and his company, Ophtec, became a leading manufacturer of IOLs.

In pioneer, news, Oct 01, 2015

(Archive) Welcome Patrick

Dr. Patrick Merz, a research biotechnologist with six years of experience, joins the David J Apple International Laboratory for Ocular Pathology as Laboratory Leader, overseeing research programs and managing facilities.

In lab, news, May 01, 2015

Opacification after rTPA

The David J Apple Lab team and UK clinicians published a study on intraocular lens opacification after intracameral injection of recombinant tissue plasminogen activator to treat inflammatory membranes following cataract surgery.

In news, publication, Mar 18, 2015

DGII Award for Mary Attia

Dr. Mary Safwat Aziz Attia, an ophthalmologist at Heidelberg University Clinic, won the "Best Paper of the Session" award at the 2015 DGII meeting for her research on multifocal IOLs using the Salzburg Reading Desk.

In research, news, Mar 11, 2015

Feast for Eye and Ear

Prof. Dr. med. Gerd Auffarth, Head of the DJApple Lab, drew a record 730 attendees to his "Medicine in the Evening" lecture on ophthalmology, sponsored by the Rhein Neckar Zeitung.

In news, Jan 25, 2015

The Ridleys visit the Lab

The Ridley Eye Foundation works to cure blindness in Nepal by providing small incision cataract surgery to those in need. The foundation collaborates with local hospitals and organizations to provide medical care and restore sight to people in remote areas.

In news, Dec 22, 2014

Boston ASCRS.

Dr. Ramin Khoramnia won the Runner-Up prize in the Cataract Complications category at the 2014 ASCRS Films Awards Ceremony for his film "CSI: Heidelberg-IOL Analysis." He also received the ASCRS Foundation's 2014 Resident Excellence Award, recognizing his outstanding performance in research, patient care, leadership, and education.

In news, Apr 30, 2014

Better vision for AMD patients.

Oculentis Lentis Mplus High Add IOL is a hydrophobic acrylic biconvex IOL which has a +8 D sector-shaped near addition resulting in 6 D of near correction at the spectacle plane and 1.5 times magnifying power. “It provides image magnification for near — quite useful for AMD patients who normally have to rely on low vision reading aids such as magnifying glasses or electronic reading desks,” Prof. Gerd U.

In clinical, news, Apr 03, 2014

Congratulations, Ramin!

Ramin Khoramnia, a Research Fellow from The Apple Lab, achieved second place in the European Board of Ophthalmology's 2013 exam, demonstrating exceptional knowledge and skills in ophthalmology.

In staff, news, Aug 29, 2013

The Legend of Albert Schweitzer

The Nobel Peace Prize is awarded annually to individuals or organizations who have made outstanding contributions to peace, arms reduction, international cooperation, and human rights. Established by Alfred Nobel's will in 1895, the prize is presented by the Norwegian Nobel Committee and has been awarded to notable figures such as Albert Schweitzer, who received the prize in 1952 for his philosophy of "Reverence for Life."

In news, Feb 22, 2013

Crossing an Ocean – the laboratory that moved

The David J Apple Lab, led by Professor Gerd U. Auffarth, has relocated from Charleston, South Carolina to the University Eye Department of the University of Heidelberg. The lab aims to create an international research center for intraocular ophthalmic devices, continuing and expanding the work initiated by David Apple.

In news, Nov 02, 2012

Moving to Heidelberg.

“For us, it is a great honour to be able to carry on the legacy of this great man,” says the CEO of the company. “We are proud to be part of the project,’ he adds, “and we are looking forward to working with the team.”

In lab, news, Sep 11, 2012

history

Two Apple cores

Dr. David J. Apple, a renowned ophthalmologist and pathologist, founded the David J. Apple Laboratory for Ophthalmic Devices Research. He trained over 200 students and doctors, known as the "Apple Korps," and made significant contributions to cataract surgery and intraocular lens (IOL) implantation. After his death in 2011, his laboratory was transferred to the University of Heidelberg, Germany, where Dr. Gerd U. Auffarth continues his work, now known as the Auffarth-Apple Korps.

In news, history, Mar 01, 2023

The 80th anniversary of David Apple

David J. Apple was a renowned ophthalmic pathologist who made significant contributions to the field of intraocular lens (IOL) research and ophthalmic surgery. He was a medical historian and biographer of Sir Harold Ridley, the inventor of the IOL. Apple founded the Center for Developing World Ophthalmology and was a pioneer in IOL research, improving the world that Ridley's invention had changed. He received numerous honors and awards for his work, including the Life Achievement Honor Award and the ASCRS Innovator's Award.

In lab, history, Sep 14, 2021

Remember 29th November!

"Today, November 29, 2020, marks the 71st anniversary of Sir Harold Ridley's first implantation of an intraocular lens (IOL) at St Thomas's Hospital in London on November 29, 1949."

In news, history, Nov 29, 2020

70th IOL anniversary

"Today marks the 70th anniversary of Sir Harold Ridley's groundbreaking implantation of the first intraocular lens (IOL) at St. Thomas's Hospital in London on November 29, 1949."

In history, lab, Nov 29, 2019

A Lab with history

David J. Apple was a renowned ophthalmic pathologist who significantly improved the world of ophthalmology through his groundbreaking research on intraocular lens (IOL) complications and ophthalmic surgery. He founded the Center for Developing World Ophthalmology and was a medical historian, biographer of Sir Harold Ridley, and a pioneer in IOL research. His work led to the development of safer and more effective IOLs, and he trained over 200 students and doctors who now hold key positions in ophthalmic education and practice worldwide.

In history, Aug 01, 2013

Why Heidelberg?

Heidelberg University is a public research university in Germany, founded in 1386. It is known for its strong research tradition, with 55 Nobel Prize winners affiliated with the university. The university has two main campuses, one in the Old Town and another in Neuenheimer Feld, which houses the medical and natural sciences faculties. Heidelberg is consistently ranked among Europe's top universities, with a strong focus on international education and research collaborations.

In history, lab, Oct 24, 2012

staff

(ARCHIVE) Welcome Lucia

Dr. Lucia Poggi, a cell biology leader, has joined the David J Apple International Laboratory for Ocular Pathology. She has a background in cellular-resolution microscopy and researches in-vivo cell biology, focusing on asymmetric cell division and fate identity acquisition during ocular development and regeneration.

In staff, news, Jul 15, 2016

(ARCHIVE) Welcome Sonja

The David J Apple International Laboratory for Ocular Pathology is a leading research center for intraocular devices, continuing the work of renowned expert David J Apple. The lab focuses on improving IOL design, materials, and implantation techniques to avoid complications.

In staff, news, Jul 01, 2016

Congratulations, Ramin!

Ramin Khoramnia, a Research Fellow from The Apple Lab, achieved second place in the European Board of Ophthalmology's 2013 exam, demonstrating exceptional knowledge and skills in ophthalmology.

In staff, news, Aug 29, 2013

clinical

Xactitude!

This study evaluates the xact Mono-EDoF ME4 IOL, a new hybrid monofocal lens with extended depth of focus, in 28 patients undergoing cataract surgery. The results show good functional outcomes for far and intermediate distance visual acuity and low levels of photic phenomena.

In clinical, news, Oct 12, 2021

Reversible Trifocality

A 49-year-old woman underwent bilateral exchange of a supplementary trifocal sulcus-fixated intraocular lens to correct a residual refractive error six months after the initial duet procedure. The exchange improved her uncorrected distance visual acuity and allowed for complete spectacle independence, demonstrating the reversibility and safety of the duet procedure.

In clinical, news, Dec 01, 2020

Dry eye drops

Evaporative dry eye (EDE) is a common condition where tears evaporate too quickly, causing discomfort, irritation, and blurred vision. It is often caused by meibomian gland dysfunction, which can be treated with warm compresses, thermal pulsation, intense pulsed light, and meibomian gland probing. EDE can also be managed with topical medications like spironolactone and azithromycin.

In clinical, news, Aug 03, 2020

Better vision for AMD patients.

Oculentis Lentis Mplus High Add IOL is a hydrophobic acrylic biconvex IOL which has a +8 D sector-shaped near addition resulting in 6 D of near correction at the spectacle plane and 1.5 times magnifying power. “It provides image magnification for near — quite useful for AMD patients who normally have to rely on low vision reading aids such as magnifying glasses or electronic reading desks,” Prof. Gerd U.

In clinical, news, Apr 03, 2014

research

Supplementary IOL calcification

Researchers analyzed explanted intraocular lenses from polypseudophakic eyes with supplementary sulcus-supported lenses, finding calcification in both capsular bag and supplementary lenses, with varying morphology and patterns related to environmental factors and comorbidities.

In lab, research, Jul 27, 2020

Visualising rays in IOLs

The study visualized and analyzed the optical performance of four intraocular lens (IOL) models using a ray propagation imaging technique and modulation transfer function (MTF) measurements. The IOLs included a monofocal, bifocal, trifocal, and extended-depth-of-focus (EDOF) lens. The results showed distinct foci for distance and near vision in the bifocal and EDOF IOLs, and three distinct foci in the trifocal IOL. The technique allowed for a qualitative assessment and comparison of light energy distribution between different IOL models.

In research, news, Feb 05, 2020

Reasons for explanting IOLs

The Apple Lab research team analyzed 200 intraocular lens (IOL) explants, finding that the main reasons for explantation were IOL opacification (76.5%) and dislocation (13.5%). Most explants were hydrophilic acrylic lenses from a single manufacturer.

In research, news, Jan 18, 2020

Small-aperture IOL results.

Researchers evaluated the visual outcomes of 13 cataract patients with a small-aperture IOL in one eye and a segmental-refractive bifocal IOL in the other, showing improved binocular visual results and minimal photic phenomena.

In research, news, Sep 12, 2019

Light scattering

Researchers at the David J Apple Lab studied glistening formation and light scattering in six hydrophobic-acrylic intraocular lenses, finding glistenings in five models but not in the Kowa IOL.

In research, publication, Sep 14, 2018

DGII Award for Mary Attia

Dr. Mary Safwat Aziz Attia, an ophthalmologist at Heidelberg University Clinic, won the "Best Paper of the Session" award at the 2015 DGII meeting for her research on multifocal IOLs using the Salzburg Reading Desk.

In research, news, Mar 11, 2015

publication

Pupil dynamics

This study compares pupil size after three different strategies for intraocular lens (IOL) fixation: anterior iris-fixation, retropupillary iris-fixation, and in-the-bag implantation. The results show that all three strategies do not impair pupil constriction in normal light conditions, but retropupillary iris-fixation results in smaller scotopic pupil sizes compared to the other two methods.

In publication, lab, Nov 26, 2021

Straylight from glistenings

Glistenings in hydrophobic acrylic intraocular lenses (IOLs) are fluid-filled microvacuoles that can negatively impact visual function. Studies have shown that severe glistenings can mildly reduce contrast sensitivity and visual acuity. The formation of glistenings is highly dependent on IOL material, with hydrophobic acrylic materials being most affected. In-vitro studies have been conducted to accelerate glistening formation and evaluate the optical quality of IOLs. Results indicate that a limited number of glistenings does not significantly affect image quality, but dense glistenings can lead to small deteriorations in optical performance.

In publication, news, Jul 01, 2019

CSI:Heidelberg Episode 2

"CSI Heidelberg Episode 2 focuses on multifocal and EDOF (Extended Depth of Focus) intraocular lens (IOL) technology, highlighting their features, benefits, and challenges.

In news, publication, Oct 01, 2018

Light scattering

Researchers at the David J Apple Lab studied glistening formation and light scattering in six hydrophobic-acrylic intraocular lenses, finding glistenings in five models but not in the Kowa IOL.

In research, publication, Sep 14, 2018

Functional results and photic phenomena with Mini WELL Ready IOL

The study evaluated the clinical outcomes of the Mini WELL Ready extended-depth-of-focus intraocular lens (EDOF-IOL) in 14 cataract patients. The lens provided good postoperative functional results at far and intermediate distances, with high rates of spectacle independence and satisfaction in everyday life. Patients reported little to no dysphotopsia, and the lens improved visual and reading acuity at reading distances.

In news, publication, Aug 28, 2018

EDOF wavelength dependence

The latest paper from the David J Apple Lab, titled "The Effect of a Spectral Filter on Visual Quality in Patients with an Extended-Depth-Of-Focus Intraocular Lens," has been accepted for publication in the American Journal of Ophthalmology. The study examines the impact of spectral filters on visual quality in patients with diffractive intraocular lenses, finding that while red filters do not improve distance vision, they can cause visual deterioration at near distances.

In publication, Aug 19, 2018

Optical Quality July 1, 2018

New research from the David J Apple Lab reveals that pars plana vitrectomy with gas injection increases the risk of secondary calcification in hydrophilic acrylic intraocular lenses, necessitating IOL exchange.

In publication, news, Jul 01, 2018

A dip into our Archives

Multifocal intraocular lenses (IOLs) have advanced significantly, offering improved visual outcomes and spectacle independence after cataract surgery. These lenses divide light into different focuses, enhancing near vision but potentially causing halos, glare, and lower contrast sensitivity. Recent research aims to optimize their optical design, and careful patient selection and surgical technique are crucial for success.

In publication, Sep 07, 2017

Hydrophilic acrylic IOLs and Lamellar keratoplasty

Researchers at the David J Apple International Laboratory for Ocular Pathology analyzed 13 hydrophilic intraocular lenses (IOLs) that became opacified after posterior lamellar keratoplasty, finding that the opacification was caused by calcium phosphate deposits on the IOL surface. This opacification significantly deteriorated the optical quality of the IOLs. The study suggests that the instillation of air or gas into the anterior chamber during these procedures increases the risk of IOL opacification, and recommends avoiding hydrophilic acrylic IOLs in patients who may require such procedures.

In news, publication, Aug 22, 2017

CSI: Heidelberg Episode 3

"CSI Heidelberg Episode 3 focuses on multifocal and extended depth-of-focus (EDOF) intraocular lens (IOL) technology, highlighting the differences and working principles of various presbyopia-correcting IOLs."

In news, publication, Aug 30, 2016

CSI:Heidelberg Episode 1

The Winner - Best Video at the annual meeting of ESCRS 2018 in Vienna. This is the first epsiode of a series about the work done in the laboratory. The first video was shot in a CSI: Crime Scene Investigation style. The video series informs the viewer how we operate.

In news, publication, Aug 30, 2016

Opacification after rTPA

The David J Apple Lab team and UK clinicians published a study on intraocular lens opacification after intracameral injection of recombinant tissue plasminogen activator to treat inflammatory membranes following cataract surgery.

In news, publication, Mar 18, 2015

pioneer

Albert Galand 1938 - 2015.

Albert Galand (1938-2015) was a pioneer in capsular IOL design and intra-capsular techniques. He developed novel capsulotomy methods, including the envelope technique, and designed lenses for capsular implantation. Galand was a strong advocate for in-the-bag fixation of IOLs and organized international meetings to promote this approach. His contributions to ophthalmology were significant, and his ideas continue to influence IOL development.

In pioneer, news, Jan 06, 2016

Jan Worst 1928 to 2015

Jan Worst, a pioneer in intraocular lens (IOL) design and co-founder of Ophtec, died on September 25, 2015, in Groningen, Netherlands. He developed the iris claw lens and phakic IOLs, and his company, Ophtec, became a leading manufacturer of IOLs.

In pioneer, news, Oct 01, 2015

innovator

Wolfgang Haigis: in memoriam

Prof. Dr. Wolfgang Haigis, a renowned physicist, passed away on October 15, 2019, at the age of 72. He was a pioneer in biometry and developed the Haigis formula, used globally for cataract surgery.

In innovator, news, Oct 18, 2019

research

EDOF IOL research

This study compares the image quality of three extended depth-of-focus (EDOF) intraocular lens models in monochromatic and polychromatic light. The results show that EDOF IOLs are more resistant to chromatic effects and provide better through-focus performance than monofocal IOLs, but differences in optical design and pupil dependency should be considered for optimal patient outcomes.

In research , news, Jan 20, 2020

News

Congratulations Max!

Maximilian Hammer, a research student at the David J Apple Lab, won the 2020 MLP Medical Excellence Scholarship in the "Science" category, a 4000-euro award for outstanding German medical students.

In Laboratory, News, Nov 26, 2020

DGII Mainz

The 34th Annual Congress of the DGII was held in Mainz, Germany, from February 13 to 15, 2020. The event featured presentations from the Apple Lab and the Eye Department in Heidelberg, with several team members winning awards for their research on intraocular lenses and optics.

In News, Feb 15, 2020

COVID 19

After Lock-down - how to re-start?

The webinar, "SIFI Global Webinar," held on May 9, 2020, discussed the challenges of restarting cataract surgery after lockdown restrictions due to the COVID-19 pandemic. The panel, consisting of seven surgeons from Asia and Europe, covered topics such as patient interview protocols, COVID-19 testing, ocular infection, and tele-ophthalmology. The webinar aimed to provide guidance on safely resuming clinical and surgical practices.

In news, COVID 19, May 11, 2020

ophthalmology

Anneke Worst (1928-2020)

Ophtec, a Dutch IOL manufacturer, was founded by Jan and Anneke Worst. Anneke Worst passed away in 2020, and the company continues to innovate with products like the Precizon Go IOL.

In ophthalmology, news, Aug 04, 2020

laboratory

Platinum Performance!

The German Congress of Ophthalmic Surgeons (DOC) in Nuremberg, Germany, on June 25, 2022, was the largest face-to-face meeting in three years with 5,400 delegates. Researchers from the David J Apple Center for Vision Research in Heidelberg won four of the seven "Conference Best Paper Awards," with Prof. Dr. med. Gerd U. Auffarth receiving the first-ever Platinum Medal.

In laboratory, news, Jun 26, 2022

The aesthetics of iris reconstruction

A study evaluated the aesthetic outcome of iris reconstruction using a custom-made artificial iris prosthesis in patients with traumatic partial or total aniridia. The results showed good aesthetic outcomes, with patients, eye doctors, and laymen rating the overall aesthetic outcome highly. Pupil centration was a key factor correlating with aesthetic satisfaction, and the artificial iris was slightly brighter than the residual iris and fellow eye iris.

In laboratory, news, Aug 18, 2020

IOL sutured to an Artificial Iris - does it affect the IOL's optics?

Researchers assessed the optical quality of monofocal intraocular lenses (IOLs) sutured to an artificial iris, finding that while the lenses' modulation transfer function (MTF) decreased slightly, the changes were clinically irrelevant.

In laboratory, news, Aug 05, 2020

Clinical

CSI: Heidelberg. Episode 4 DMEK with EndoArt®

The EndoArt, an artificial endothelial replacement membrane, has shown promising results in treating chronic corneal edema. This dome-shaped, 50-μm thick implant is made of a flexible, hydrophilic acrylic material and is designed to replace the diseased endothelium. It is implanted using the "push through" technique and has been shown to significantly reduce central corneal thickness and improve visual acuity in patients. The device has several advantages over traditional donor tissue, including being off-the-shelf, non-biological, and not requiring immunosuppressive treatment.

In news, Clinical, Oct 11, 2020

Pinhole Xtrafocus

Heidelberg University Eye Clinic successfully treated a patient with radial keratotomy 22 years prior using a Morcher Xtrafocus lens, correcting fluctuating residual refraction after cataract surgery.

In Clinical, news, Sep 01, 2020

event

4. Heidelberger Helmholtztage, 27 & 28 November

The 4th Heidelberg Helmholtz Days will take place on November 27-28, 2020, as a hybrid meeting at the Palatin Congress and Cultural Centre in Wiesloch, Heidelberg. The event will have 150 in-person attendees and offer live online lectures, with a focus on current topics related to Hermann Helmholtz's work.

In event, news, Oct 03, 2020

Laboratory

Congratulations Max!

Maximilian Hammer, a research student at the David J Apple Lab, won the 2020 MLP Medical Excellence Scholarship in the "Science" category, a 4000-euro award for outstanding German medical students.

In Laboratory, News, Nov 26, 2020

Research

Glistening through the years

Study quantifies the decrease in glistening formation in Alcon's hydrophobic acrylic intraocular lenses over the past three decades, with the new Clareon material showing the lowest number of microvacuoles.

In Research, History, Feb 05, 2021

History

Glistening through the years

Study quantifies the decrease in glistening formation in Alcon's hydrophobic acrylic intraocular lenses over the past three decades, with the new Clareon material showing the lowest number of microvacuoles.

In Research, History, Feb 05, 2021

Clinical

IOL fixed to the capsulotomy!

A European multicenter trial found that a new IOL fixed to a femtosecond laser-made capsulotomy resulted in less decentration, tilt, and rotation, providing excellent visual and refractive outcomes over 12 months.

In Clinical , news, Feb 27, 2021

research on silicone oil

Polyimide cannulas

Researchers compared the injection times of high-viscosity silicone oils using polyimide and metal cannulas. Polyimide cannulas significantly reduced injection times, allowing for the use of ultra-high-viscosity oils, and prewarming the oil further decreased injection times.

In research on silicone oil, news, Feb 06, 2022

Introducing Dynamic Stimulation Aberrometry

Researchers introduced dynamic stimulation aberrometry (DSA) to objectively measure binocular accommodation in 91 patients, finding that accommodative amplitude decreases with age and that DSA records pupil motility dynamically.

In lab, news, , Apr 29, 2023

lab news

Team VitreoSub is a winner!

The provided sources discuss various topics related to the vitreous body and retinal care. The vitreous body is a gel-like substance that fills the posterior chamber of the eye, maintaining the eyeball's shape. Vitreous Retina Macula Consultants of New York (VRMNY) is involved in clinical trials for wet age-related macular degeneration and diabetic macular edema, and their doctors have spoken at conferences on multimodal imaging and ophthalmic ultrasonography. Healio provides news articles, videos, and podcasts on retinal conditions, including the use of multimodal imaging, novel VEGF inhibitors, and mitochondrial stabilizers. Vitreoretinal Consultants of NY shares updates on their practice and announces the win of the Science4Life Venture Cup 2024 by their team, VitreoSub, for developing vitreous body replacement strategies.

In lab news, Dec 13, 2023

DOG 2023 -Group Photo

The annual congress of the German Society of Ophthalmology (D.O.G.) took place on September 29, 2023, in Berlin, featuring a group photo of ophthalmologists from hospitals, medical centers, and research centers, including the David J Apple Center for Vision Research.

In lab news, Sep 29, 2023

APACRS LIM Lecture

Prof. Gerd U. Auffarth delivered the 2023 APACRS LIM Lecture, discussing current and future developments in intraocular implants with new materials at the 35th APACRS Annual Meeting in Singapore.

In lab news, Aug 12, 2023

Enlarged incisions – but why?

Researchers analyzed 409 incisions from 13 IOL injector models to identify factors affecting final incision size in cataract surgery, finding that injector tip diameter, preoperative incision size, insertion depth, and incision length significantly impact final incision size.

In lab news, Jun 29, 2023

DOC23 Success

The David J Apple Laboratory celebrates success at the 35th International Congress of German Ophthalmic Surgery (DOC) in Nuremberg, where research fellows Leonie Britz and Max Hammer won "Best Paper of Session" Awards for their lectures.

In lab news, Jun 20, 2023

clinical news

The safety of Reversible Trifocality.

The paper "Rotational Stability of Toric Capsular Bag–Fixated Intraocular Lenses in Duet Procedure for Reversible Trifocality" evaluates the long-term rotational stability of toric intraocular lenses in polypseudophakic eyes. The study found that the presence of a second lens in the sulcus did not affect the rotational stability of the first lens in the capsular bag.

In clinical news, Oct 14, 2023

Lab news

Oil and Lenses don't mix

Researchers studied how silicone oil adhesion to intraocular lenses (IOLs) affects straylight, finding significant increases in straylight. The study also showed that the cleaning solution F4H5 can reverse straylight values, but surface changes remain.

In Lab news, Silicone oIl study, Nov 26, 2023

Silicone oIl study

Oil and Lenses don't mix

Researchers studied how silicone oil adhesion to intraocular lenses (IOLs) affects straylight, finding significant increases in straylight. The study also showed that the cleaning solution F4H5 can reverse straylight values, but surface changes remain.

In Lab news, Silicone oIl study, Nov 26, 2023

Lab research

New IOL material - xPIB

Researchers have developed a novel intraocular lens (IOL) made of crosslinked polyisobutylene (xPIB), which showed promising results in terms of material quality and optical performance. The Eyedeal lens demonstrated lower glistening density and a higher contact angle compared to the AcrySof lens, a widely used control. The study suggests that xPIB could be a suitable material for IOLs, with clinical trials already underway in China and planned for Europe.

In Lab research, Mar 11, 2024

lab research

EndoArt® : 5 years

Heidelberg 18.06.2024. Five years ago, on 18th June 2019, I performed the first human implantation of the EndoArt® artificial DMEK-Implant (made by EyeYon Medical) at our Heidelberg U...

In lab research, clinical research, Jun 18, 2024

Predicting emulsification in Silicone Oil

Researchers studied straylight in explanted silicone oil samples to predict emulsification, finding increased straylight in samples from patients with visible oil droplets and specific indications, suggesting it as an early indicator for timely silicone oil removal.

In lab research, May 28, 2024

A rare case of Calcification

A rare case of intraocular lens (IOL) calcification in a patient with Ehlers-Danlos syndrome was studied, highlighting the importance of considering patient host factors in IOL selection.

In lab research, May 27, 2024

clinical research

EndoArt® : 5 years

Heidelberg 18.06.2024. Five years ago, on 18th June 2019, I performed the first human implantation of the EndoArt® artificial DMEK-Implant (made by EyeYon Medical) at our Heidelberg U...

In lab research, clinical research, Jun 18, 2024