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Website now available in German

Our website has been translated into German.

In Lab News, Jul 25, 2026
Website now available in German - Article thumbnail
Visiting Research Professors

Awards to two Visiting Research Professors

In Lab News, Jun 30, 2026
Visiting Research Professors - Article thumbnail
DOC 2026

Heidelberg Prizewinners at DOC 2026

In Lab News, Jun 21, 2026
DOC 2026 - Article thumbnail
Recommendations on IOL exchange.

Guidelines for Intraocular Lens Exchange Due to Material Changes

In Publications, Jun 11, 2026
Recommendations on IOL exchange. - Article thumbnail
Injector Force

A laboratory analysis of the variation in resistance force during intraocular lenses injection by modern injectors and assessment of damage to the injector.

In Research, May 11, 2026
Injector Force - Article thumbnail
AH Cytokine and Chemokine changes after FLACS

A study of postoperative inflammation after femtosecond laser-assisted cataract surgery showed that compared that to conventional phacoemulsification, inflammatory and oxidative stress mediators were increased in concentration in the aqueous humor.

In Research, Jan 30, 2026
AH Cytokine and Chemokine changes after FLACS - Article thumbnail
2025: 57+ publications

2025:57+ publications from the Heidelberg University Hospital Eye Department and the David J Apple Centre for Vision Research.

In Publications, Dec 31, 2025
2025: 57+ publications - Article thumbnail
2025 - Good News!

Good news to end 2025: the first African country to eliminate river blindness: the Republic of Niger leads the way.

In Lab News, Dec 31, 2025
2025 - Good News! - Article thumbnail
Refining mini-monovision

In a laboratory study, both Acunex Quantum and RayOne EMV are suitable for mini-monovision. ### Happy Christmas from the Apple Lab!

In Research, Dec 24, 2025
Refining mini-monovision - Article thumbnail
Artiplus and IPCL

Laboratory study of Ophtec's Artisan versus the Care Group's IPCL

In Research, Oct 20, 2025
Artiplus and IPCL - Article thumbnail
Vivity and PureSee

EDoF lenses allow cataract and refractive-lens-exchange patients to have improved intermediate-distance vision. The lenses are made of different materials that have different chemical and physical properties. Their optical design is also different. We compared them in an optical quality analysis.

In Research, Jul 24, 2025
Vivity and PureSee - Article thumbnail
Safety in IOL exchange

We set out to study IOL exchange in patients who had IOL complications but otherwise had healthy eyes and we found visual and refractive outcomes were generally good. Changing the lens does not cause a significant change in aberrations. Intra- and postoperative complications were mostly mild and ...

In Research, Jun 30, 2025
Safety in IOL exchange - Article thumbnail
Simulating IOL vision before implanting a lens

IOL simulators, where the patient can experience vision through IOLs prior to IOL implantation, are gaining interest among researchers and clinicians. We examined the correlation between one look-through simulator and the optical properties of modern IOLs, that we measured using an IOL metrology ...

In Research, Jun 25, 2025
Simulating IOL vision before implanting a lens - Article thumbnail
Exact and Symfony

We compared two hybrid refractive-diffractive IOLs with enhanced depth of focus.

In Research, May 20, 2025
Exact and Symfony - Article thumbnail
New Certificate

New certificate ISO9001:2015

In Lab News, Mar 07, 2025
New Certificate - Article thumbnail
DGII 2025 prizewinning papers

Five prizewinning papers from Heidelberg at this year's DGII meeting.

In Lab News, Feb 15, 2025
DGII 2025 prizewinning papers - Article thumbnail
An objective decision criterion for IOL exchange

Counselling after IOL calcification

In Research, Feb 09, 2025
An objective decision criterion for IOL exchange - Article thumbnail
How was the Ridley-Rayner IOL made?

Who were the Rayner men who designed and made the early IOLs?

In History, Nov 29, 2024
How was the Ridley-Rayner IOL made? - Article thumbnail
Flies, Blinding Worms, Spitting snakes!

Ridley's 1944 radio broadcast about his field trip to Funsi, (RiverBlindness is eradicated now in parts of Ghana) and Ridley's snake venom paper

In History, Nov 26, 2024
Flies, Blinding Worms, Spitting snakes! - Article thumbnail
A Novice in Tropical Ophthalmology

Harold Ridley's field work expedition in Ghana during World War Two

In History, Sep 20, 2024
A Novice in Tropical Ophthalmology - Article thumbnail
Fine by name and by nature

Remembering Howard Fine

In In Memoriam, Sep 09, 2024
Fine by name and by nature - Article thumbnail
Review of modern injectors

Review of IOL injectors

In Research, Aug 15, 2024
Review of modern injectors - Article thumbnail
CAIRS

a 35-year old male presented to our keratoconus clinic complaining of bilateral reduced vision , despite spectacle correction due to significant astigmatism . his occupation as a welder with heavy exposure to a dusty environment made him an unsuitable candidate for contact lenses . the patient's ...

In Clinical, Jul 11, 2024
CAIRS - Article thumbnail
Harold Ridley's birthday, 10 July

2024 marks the 75th anniversary of the first intraocular lens manufactured by Rayner in 1949. Sir Harold Ridley was born in Kibworth, a village in Leicestershire in the English Midlands, on 10th July 1906. He was the elder son of Nicholas Charles Ridley and Margaret (née Parker)

In History, Jul 10, 2024
Harold Ridley's birthday, 10 July - Article thumbnail
Predicting emulsification in Silicone Oil

Researchers studied straylight in explanted silicone oil samples to predict emulsification, finding increased straylight in samples from patients with visible oil droplets and specific indications, suggesting it as an early indicator for timely silicone oil removal.

In Research, May 28, 2024
Predicting emulsification in Silicone Oil - Article thumbnail
A rare case of Calcification

A rare case of intraocular lens (IOL) calcification in a patient with Ehlers-Danlos syndrome was studied, highlighting the importance of considering patient host factors in IOL selection.

In Research, May 27, 2024
A rare case of Calcification - Article thumbnail
New IOL material - xPIB

Researchers have developed a novel intraocular lens (IOL) made of crosslinked polyisobutylene (xPIB), which showed promising results in terms of material quality and optical performance. The Eyedeal lens demonstrated lower glistening density and a higher contact angle compared to the AcrySof lens...

In Research, Mar 11, 2024
New IOL material - xPIB - Article thumbnail
Oil and Lenses don't mix

Researchers studied how silicone oil adhesion to intraocular lenses (IOLs) affects straylight, finding significant increases in straylight. The study also showed that the cleaning solution F4H5 can reverse straylight values, but surface changes remain.

In Research, Nov 26, 2023
Oil and Lenses don't mix - Article thumbnail
The safety of Reversible Trifocality.

The paper "Rotational Stability of Toric Capsular Bag–Fixated Intraocular Lenses in Duet Procedure for Reversible Trifocality" evaluates the long-term rotational stability of toric intraocular lenses in polypseudophakic eyes. The study found that the presence of a second lens in the sulcus did no...

In Clinical, Oct 14, 2023
The safety of Reversible Trifocality. - Article thumbnail
DOG 2023 -Group Photo

The annual congress of the German Society of Ophthalmology (D.O.G.) took place on September 29, 2023, in Berlin, featuring a group photo of ophthalmologists from hospitals, medical centers, and research centers, including the David J Apple Center for Vision Research.

In Lab News, Sep 29, 2023
DOG 2023 -Group Photo - Article thumbnail
Comparing Multisert and AutonoMe.

Comparing Multisert and AutonoMe IOL injectors, a study found both allowed safe implantation, but Multisert showed more consistent behavior and less injector damage.

In Research, Sep 26, 2023
Comparing Multisert and AutonoMe. - Article thumbnail
APACRS LIM Lecture

Prof. Gerd U. Auffarth delivered the 2023 APACRS LIM Lecture, discussing current and future developments in intraocular implants with new materials at the 35th APACRS Annual Meeting in Singapore.

In Lab News, Aug 12, 2023
APACRS LIM Lecture - Article thumbnail
Overcoming implantation challenges with SING IMT

The SING IMT is a second-generation implantable miniature telescope designed to improve visual acuity and quality of life in patients with late-stage age-related macular degeneration (AMD). It features a smaller incision and improved surgical techniques compared to its predecessor. The device has...

In Clinical, Aug 01, 2023
Overcoming implantation challenges with SING IMT - Article thumbnail
Enlarged incisions – but why?

Researchers analyzed 409 incisions from 13 IOL injector models to identify factors affecting final incision size in cataract surgery, finding that injector tip diameter, preoperative incision size, insertion depth, and incision length significantly impact final incision size.

In Research, Jun 29, 2023
Enlarged incisions – but why? - Article thumbnail
Vergrößerte Inzisionen – aber warum?

Forschende analysierten 409 Inzisionen von 13 IOL-Injektormodellen, um Faktoren zu bestimmen, die die endgültige Inzisionsgröße bei der Kataraktoperation beeinflussen, und fanden, dass Injektorspitzendurchmesser, präoperative Inzisionsgröße, Einführtiefe und Inzisionslänge die endgültige Inzision...

In Research, Jun 29, 2023
Vergrößerte Inzisionen – aber warum? - Article thumbnail
DOC23 Success

The David J Apple Laboratory celebrates success at the 35th International Congress of German Ophthalmic Surgery (DOC) in Nuremberg, where research fellows Leonie Britz and Max Hammer won "Best Paper of Session" Awards for their lectures.

In Lab News, Jun 20, 2023
DOC23 Success - Article thumbnail
Introducing Dynamic Stimulation Aberrometry

Researchers introduced dynamic stimulation aberrometry (DSA) to objectively measure binocular accommodation in 91 patients, finding that accommodative amplitude decreases with age and that DSA records pupil motility dynamically.

In Research, Apr 29, 2023
Introducing Dynamic Stimulation Aberrometry - Article thumbnail
We're Recruiting!

The David J Apple Center for Vision Research is recruiting a student researcher to work on new projects involving material science applications for posterior segment ocular disease. The position involves laboratory bench research, rheological analyses, and Wet Lab surgery projects, with the possi...

In Lab News, Jan 23, 2023
We're Recruiting! - Article thumbnail
Merci beaucoup Philippe

Professor Philippe Sourdille delivered the 1st David J. Apple MD Memorial Lecture, "Events I Have Witnessed Over Many Years," at the University-Eye-Clinic in Heidelberg, Germany, sharing a fascinating journey through decades of ophthalmic research and technology.

In Lab News, Jul 18, 2022
Merci beaucoup Philippe - Article thumbnail
Jan Worst 1928 to 2015

Jan Worst, a pioneer in intraocular lens (IOL) design and co-founder of Ophtec, died on September 25, 2015, in Groningen, Netherlands. He developed the iris claw lens and phakic IOLs, and his company, Ophtec, became a leading manufacturer of IOLs.

In In Memoriam, Sep 29, 2015
Jan Worst 1928 to 2015 - Article thumbnail
Welcome

The David J Apple® Laboratory continues the pioneering work of Dr. David Apple which focuses on intraocular lens research and improving cataract surgery techniques.

In Lab News, Oct 25, 2013
Welcome - Article thumbnail
The Legend of Albert Schweitzer

Albert Schweitzer (1875 – 1965) was multi-talented: a theologian, a doctor of medicine, a church organist, philosopher, pacifist and a philanthropist. Schweitzer received the 1952 Nobel Peace Prize in 1952 for his contribution to philosophy of "Reverence for Life."

In History, Feb 21, 2013
The Legend of Albert Schweitzer - Article thumbnail
Why Heidelberg?

Heidelberg University is a public research university in Germany, founded in 1386. It is known for its strong research tradition, with 55 Nobel Prize winners affiliated with the university. The university has two main campuses, one in the Old Town and another in Neuenheimer Feld, which houses the...

In History, Oct 24, 2012
Why Heidelberg? - Article thumbnail

sticky

Website now available in German

Our website has been translated into German.

In Lab News, Jul 25, 2026
Website now available in German - Article thumbnail
Recommendations on IOL exchange.

Guidelines for Intraocular Lens Exchange Due to Material Changes

In Publications, Jun 11, 2026
Recommendations on IOL exchange. - Article thumbnail
Two Apple cores

The core of the laboratory is the people who do the research. While David Apple was alive, he called his researchers the **Apple Korps**. Now one can talk of a New Generation of **Auffarth-Apple Korps**.

In History, Mar 01, 2023
Two Apple cores - Article thumbnail
Welcome

The David J Apple® Laboratory continues the pioneering work of Dr. David Apple which focuses on intraocular lens research and improving cataract surgery techniques.

In Lab News, Oct 25, 2013
Welcome - Article thumbnail

feature

Team VitreoSub is a winner!

The provided sources discuss various topics related to the vitreous body and retinal care. The vitreous body is a gel-like substance that fills the posterior chamber of the eye, maintaining the eyeball's shape. Vitreous Retina Macula Consultants of New York (VRMNY) is involved in clinical trials ...

In Lab News, Dec 13, 2023
Team VitreoSub is a winner! - Article thumbnail