Heidelberg, New Year’s Eve. 2025/2026.
New Year’s Eve is a good time to look back at what was achieved in 2025. A reliable metric is to look at the number of publications in which the majority of the authors are from the Heidelberg University Hospital Eye Department and the David J Apple Centre for Vision Research. I list here the search results using key authors’ names on Pubmed (the site of the National Center for Biotechnology Information at the U.S. National Library of Medicine.) There were at least 57 publications, many in the most prestigious peer-reviewed journals.
While I am immensely proud of this achievement and I thank my colleagues for their hard work and dedication, I also see it sets a target to exceed in 2026 - a goal which we are more than ready to take on. I wish you all a Happy New Year,
Best wishes
Gerd
Prof. Dr. med. Gerd U. Auffarth MD, FEBO
Eye Department Chairman & Director of The David J Apple Center for Vision Research.
List of 2025 publications
- Die neuen ANTI-VEGF Präparate: Evolution oder Revolution? Khoramnia R, Kessler LJ, Auffarth GU, Albrecht M. Klin Monbl Augenheilkd. 2025 Mar;242(3):193-195. doi: 10.1055/a-2370-7389. Epub 2025 Feb 5. PMID: 39909071 German. No abstract available.
- Visual and Topographic Outcomes After Corneal Allogeneic Intrastromal Ring Segments for Keratoconus: A Systematic Review and Meta-Analysis. Friedrich M, Auffarth GU, Soiberman U, Augustin VA, Khoramnia R, Son HS. Am J Ophthalmol. 2025 Aug;276:81-91. doi: 10.1016/j.ajo.2025.03.028. Epub 2025 Mar 27. PMID: 40157443
- [An (Un)Classical Venous Event]. Reitemeyer EV, Hammer M, Schmidt-Bacher A, Auffarth GU, Feltgen N. Klin Monbl Augenheilkd. 2025 Sep;242(9):878-880. doi: 10.1055/a-2682-2123. Epub 2025 Sep 18. PMID: 40967231 German. No abstract available.
- [Corneal allogeneic intrastromal ring segments]. Son HS, Hüfner L, Auffarth GU, Friedrich M, Augustin VA. Ophthalmologie. 2025 Dec 11. doi: 10.1007/s00347-025-02355-y. Online ahead of print. PMID: 41381895 Review. German.
- Cataract surgery in the extremely small eye: morphology, comorbidities and outcomes in 300 eyes. Hammer M, Teich L, Friedrich M, Reitemeyer E, Britz L, Khoramnia R, Yildirim TM, Auffarth GU. Br J Ophthalmol. 2025 Jul 22;109(8):917-924. doi: 10.1136/bjo-2024-326998. PMID: 40015941 Free PMC article.
- [Mysterious scotomas after cesarean section]. Hammer M, Junker N, Reitemeyer EV, Auffarth GU, Augustin VA, Feltgen N. Klin Monbl Augenheilkd. 2025 Dec;242(12):1165-1168. doi: 10.1055/a-2745-9019. Epub 2025 Dec 12. PMID: 41386255 German. No abstract available.
- Comparison of clinical outcomes between different combinations of hybrid multifocal, extended-depth-of-focus and enhanced monofocal intraocular lenses. Kim B, Son HS, Khoramnia R, Auffarth GU, Choi CY. Br J Ophthalmol. 2025 Apr 22;109(5):565-571. doi: 10.1136/bjo-2024-325181. PMID: 39658143 Clinical Trial.
- Evaluation of Clareon Vivity and PureSee intraocular lenses: optical quality, depth of focus and misalignment effects. Niknahad A, Wu Z, Son HS, Auffarth GU, Khoramnia R, Łabuz G. Sci Rep. 2025 Jul 24;15(1):26943. doi: 10.1038/s41598-025-07970-y. PMID: 40707598 Free PMC article.
- Review of Mix-and-Match Approach and Binocular Intraocular Lens Systems. Naujokaitis T, Łabuz G, Khoramnia R, Auffarth GU. J Clin Med. 2025 Jun 16;14(12):4263. doi: 10.3390/jcm14124263. PMID: 40566008 Free PMC article. Review.
- Corneal Allogeneic Intrastromal Ring Segments (CAIRS): The New Kid on the Block. Son HS, Augustin VA, Friedrich M, Yildirim TM, Khoramnia R, Auffarth GU. Klin Monbl Augenheilkd. 2025 Aug;242(8):803-806. doi: 10.1055/a-2621-5109. Epub 2025 May 26. PMID: 40419240 Review. English, German.
- Vision degrading myodesopsia from vitreous floaters in the young: An important aspect of myopia. Albrecht M, Auffarth GU, Friedrich M, Kessler LJ, Khoramnia R. Surv Ophthalmol. 2025 Mar-Apr;70(2):265-282. doi: 10.1016/j.survophthal.2024.10.001. Epub 2024 Oct 16. PMID: 39424075 Review.
- Prospective Intraindividual Comparison of Automated Customized Ray-Tracing-Guided versus Wavefront-Optimized LASIK. Khoramnia R, Naujokaitis T, Blöck L, Fabian K, Kessler LJ, Łabuz G, Auffarth GU. Ophthalmology. 2025 Oct;132(10):1169-1179. doi: 10.1016/j.ophtha.2025.05.025. Epub 2025 Jun 5. PMID: 40482723 Clinical Trial.
- Lens opacity as a predictor of retinal vasculature change following cataract surgery. Mackenbrock LHB, Xu ATL, Łabuz G, Augustin VA, Yildirim TM, Auffarth GU, Khoramnia R. Sci Rep. 2025 Sep 25;15(1):32928. doi: 10.1038/s41598-025-19037-z. PMID: 40999114 Free PMC article.
- Cataract Surgery and DMEK: Decision-making and the Timing of the Respective Interventions. Augustin VA, Friedrich M, Son HS, Yildirim TM, Auffarth GU, Khoramnia R. Klin Monbl Augenheilkd. 2025 Aug;242(8):807-812. doi: 10.1055/a-2650-7436. Epub 2025 Aug 21. PMID: 40840456 Review. English, German.
- Optical Differentiation of Presbyopia-Correcting Intraocular Lenses With Improved Intermediate Vision From a Single Manufacturer. Son HS, Łabuz G, Wu Z, Choi CY, Khoramnia R, Auffarth GU, Tandogan T. J Refract Surg. 2025 Oct;41(10):e1098-e1105. doi: 10.3928/1081597X-20250805-05. Epub 2025 Oct 1. PMID: 41065747
- Postoperative Adjustment of Implanted Corneal Allogeneic Intrastromal Ring Segments (CAIRS) to Improve Visual and Topographic Outcomes. Jacob S, Agarwal A, Awwad ST, Son HS, Auffarth GU, Abraham R, Narasimhan S. J Refract Surg. 2025 Aug;41(8):e814-e821. doi: 10.3928/1081597X-20250515-05. Epub 2025 Aug 1. PMID: 40778862
- Polypseudophakia: from “Piggyback” to supplementary sulcus-fixated IOLs. Khoramnia R, Kahraman G, Amon M, Łabuz G, Baur ID, Auffarth GU. Graefes Arch Clin Exp Ophthalmol. 2025 Mar;263(3):603-624. doi: 10.1007/s00417-024-06618-3. Epub 2024 Sep 11. PMID: 39259300 Free PMC article. Review.
- Long-Term Observations of the First Human Implantation of an Artificial Endothelial Layer for Endothelial Dysfunction: A Pilot Study. Son HS, Augustin VA, Eberhart CG, Friedrich M, Reitemeyer E, Henningsen N, Hassel O, Blöck L, Auffarth GU. Cornea. 2025 Aug 15. doi: 10.1097/ICO.0000000000003972. Online ahead of print. PMID: 40815070
- Preoperative edema severity affects outcomes after Descemet membrane endothelial keratoplasty for Fuchs endothelial corneal dystrophy: a cohort study. Friedrich M, Son HS, Lind J, Hammer M, Chychko L, Yildirim TM, Auffarth GU, Augustin VA. Eye Vis (Lond). 2025 Mar 1;12(1):9. doi: 10.1186/s40662-025-00425-5. PMID: 40022251 Free PMC article.
- Comparison of Visual Acuity Outcomes of Enhanced Monofocal Versus Standard Monofocal Intraocular Lenses from a Randomized, Multicenter, Active-Controlled Trial. Ang RET, Khoramnia R, Uy HS, Hoffmann P, Anello RD, Zalewski D, Januschowski K, de Arriba Palomero P, Böhringer D, Barberá MI, Bertelmann E, Cisiecki S, Dick HB, Lorenz K, Auffarth GU, Ruiz-Mesa R, Relucio AS. J Refract Surg. 2025 Apr;41(4):e300-e309. doi: 10.3928/1081597X-20250218-01. Epub 2025 Apr 1. PMID: 40197064 Clinical Trial.
- [Emerging technology for retinal function testing: two-photon microperimetry]. Niknahad A, Zielińska A, Auffarth GU, Son HS, Lee H, Khoramnia R, Łabuz G. Ophthalmologie. 2025 Dec 4. doi: 10.1007/s00347-025-02349-w. Online ahead of print. PMID: 41345313 Review. German.
- [Evidence-based approach for premium intraocular lenses: management of postoperative dissatisfaction]. Baur ID, Mueller A, Łabuz G, Auffarth GU, Khoramnia R. Ophthalmologie. 2025 Sep;122(9):674-684. doi: 10.1007/s00347-025-02253-3. Epub 2025 Jun 13. PMID: 40512436 Review. German.
- Refining mini-monovision with monofocal plus intraocular lenses. Naujokaitis T, Auffarth GU, Wu Z, Cuéllar F, Khoramnia R, Łabuz G. Graefes Arch Clin Exp Ophthalmol. 2025 Nov 8. doi: 10.1007/s00417-025-07013-2. Online ahead of print. PMID: 41204996 No abstract available.
- The diagnostic potential of aqueous humor: Unlocking ocular and systemic insights. Chychko L, Son HS, Friedrich M, Yildirim TM, Auffarth GU, Augustin VA. Surv Ophthalmol. 2025 Dec 17:S0039-6257(25)00231-0. doi: 10.1016/j.survophthal.2025.12.004. Online ahead of print. PMID: 41419165 Review.
- [Transplantation of a corneal allogeneic intrastromal ring segment (CAIRS) for treatment of keratectasia]. Son HS, Augustin VA, Khoramnia R, Jacob S, Friedrich M, Auffarth GU. Ophthalmologie. 2025 Aug;122(8):646-651. doi: 10.1007/s00347-025-02254-2. Epub 2025 Jun 12. PMID: 40506651 Review. German.
- [Secondary calcification of a multifocal additive intraocular lens]. Mackenbrock LHB, Yildirim TM, Auffarth GU, Khoramnia R. Ophthalmologie. 2025 Apr;122(4):257. doi: 10.1007/s00347-025-02203-z. Epub 2025 Feb 24. PMID: 39992378 German. No abstract available.
- Using a look-through simulator to analyze the correlation between functional and optical properties of intraocular lenses. Wu Z, Zielińska A, Auffarth GU, Rayamajhi A, Britz L, Khoramnia R, Łabuz G. J Opt Soc Am A Opt Image Sci Vis. 2025 Jun 1;42(6):C6-C12. doi: 10.1364/JOSAA.559739. PMID: 40792919
- [Ocular side effects of pembrolizumab : Bilateral central serous retinal detachment and papillitis]. Friedrich M, Bagautdinov D, Yildirim TM, Augustin VA, Khoramnia R, Auffarth GU, Son HS. Ophthalmologie. 2025 Aug 1. doi: 10.1007/s00347-025-02287-7. Online ahead of print. PMID: 40748370 German. No abstract available.
- Methotrexate-Loaded Liposomal Formulation Enables 6-Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model. Hammer M, Skrzypczyk L, Wohlfart S, Ackermann BC, Geisweid L, Pohl SW, Karaivanova M, Herth J, Augustin VA, Studier-Fischer A, Sackmann T, Kaulen L, Steyer A, Mier W, Steel DH, Xue K, Auffarth GU, Uhl P. Adv Healthc Mater. 2025 Sep 25:e03230. doi: 10.1002/adhm.202503230. Online ahead of print. PMID: 40999813
- Quantitative spatial analysis of crystallin proteins in human lens epithelial cells. Cristoforetti A, Baldessari G, Chychko L, Chust IB, Sartori S, Schickhardt S, Ravelli F, Bertoluzza S, Carl M, Sel S, Auffarth GU, Poggi L. Sci Rep. 2025 Oct 3;15(1):34552. doi: 10.1038/s41598-025-17896-0. PMID: 41044127 Free PMC article.
- An analysis of heavy silicone oil treatment for inferior proliferative vitreoretinopathy. Hammer M, Ie A, Eibenberger K, Auffarth GU, Xue K. BMC Ophthalmol. 2025 Jan 22;25(1):38. doi: 10.1186/s12886-024-03834-7. PMID: 39844136 Free PMC article.
- Bubble-graft coverage after Descemet Membrane Endothelial Keratoplasty depending on gaze angle. Friedrich M, Son HS, Buhl RC, Meyer CM, Yildirim TM, Khoramnia R, Auffarth GU, Augustin VA. Eur J Ophthalmol. 2025 Mar;35(2):504-510. doi: 10.1177/11206721241267277. Epub 2024 Aug 9. PMID: 39119830 Free PMC article.
- A new method for analyzing glistenings in hydrophobic acrylic intraocular lenses. Göktepe MC, Yildirim TM, Łabuz G, Devogelaere T, Auffarth GU, Khoramnia R. Sci Rep. 2025 May 21;15(1):17661. doi: 10.1038/s41598-025-00137-9. PMID: 40399364 Free PMC article.
- F4H5 Alleviates Increased Outflow Resistance Induced by Emulsified Silicone Oil In Vitro. Muuss M, Karaivanova M, Skrzypczyk L, Wohlfart S, Herth J, Uhl P, Auffarth GU, Hammer M. Invest Ophthalmol Vis Sci. 2025 Aug 1;66(11):21. doi: 10.1167/iovs.66.11.21. PMID: 40778700 Free PMC article.
- An in-depth characterization of development-related electroretinographical and morphological changes in Landrace pigs. Skrzypczyk L, Ackermann BC, Augustin VA, Rahn U, Uhl P, Auffarth GU, Hammer M. Doc Ophthalmol. 2025 Dec;151(3):219-228. doi: 10.1007/s10633-025-10050-1. Epub 2025 Sep 25. PMID: 40993473 Free PMC article.
- Objective Evaluation and Comparison of Diffractive versus Refractive Phakic Intraocular Lenses for Presbyopia Correction. Zielinska A, Niknahad A, Labuz G, Wu Z, Son HS, Auffarth GU, Khoramnia R. Clin Ophthalmol. 2025 Oct 14;19:3783-3792. doi: 10.2147/OPTH.S539090. eCollection 2025. PMID: 41111597 Free PMC article.
- Performance of the First Spiral Refractive Intraocular Lens for Continuous Full Range of Vision. Abela-Formanek C, Amon M, Auffarth GU, Bostancı B, Carones F, Corbett D, Ferreira TB, Mantry S, Saad A, Llovet F, Barsam A. J Refract Surg. 2025 Nov;41(11):e1213-e1222. doi: 10.3928/1081597X-20250829-01. Epub 2025 Nov 1. PMID: 41212955
- Ray Visualization and Through-Focus Optical Quality of Diffractive Enhanced Monofocal and Extended-Depth-of-Focus Intraocular Lenses. Baur ID, Khoramnia R, Son HS, Auffarth GU, Łabuz G. Clin Ophthalmol. 2025 May 21;19:1673-1682. doi: 10.2147/OPTH.S520086. eCollection 2025. PMID: 40417136 Free PMC article.
- Early silicone oil opacification in the absence of emulsification is caused by an increased level of silicone dioxide. Hammer M, Britz L, Böhmann MB, Herbster L, Muuss M, Herth J, Cionoiu S, Krisp H, Spitzer MS, Wohlfart S, Uhl P, Auffarth GU. Retina. 2025 Mar 1;45(3):491-500. doi: 10.1097/IAE.0000000000004324. PMID: 39527946
- Immediate sequential corneal allogeneic intrastromal ring segment transplantation and cataract surgery. Auffarth GU, Augustin VA, Kilic A, Khoramnia R, Friedrich M, Son HS. Am J Ophthalmol Case Rep. 2025 Jul 22;39:102398. doi: 10.1016/j.ajoc.2025.102398. eCollection 2025 Sep. PMID: 40756998 Free PMC article.
- [New tissue-additive procedures to improve vision in keratoconus]. Hüfner L, Augustin VA, Auffarth GU, Friedrich M, Son HS. Ophthalmologie. 2026 Jan 3. doi: 10.1007/s00347-025-02370-z. Online ahead of print. PMID: 41483160 Review. German.
- Visual and ultrastructural analysis after splitting of recipient’s Descemet membrane during Descemet membrane endothelial keratoplasty. Friedrich M, Lind J, Son HS, Yildirim TM, Auffarth GU, Augustin VA. Eye (Lond). 2025 Aug;39(11):2307-2313. doi: 10.1038/s41433-025-03872-5. Epub 2025 May 27. PMID: 40425832 Free PMC article.
- Quantitative in vivo assessment of intraocular lens calcification: correlation between OCT opacity and straylight measurement. Mackenbrock LHB, Łabuz G, Henningsen N, Auffarth GU, Khoramnia R, Yildirim TM. J Cataract Refract Surg. 2025 Aug 1;51(8):666-671. doi: 10.1097/j.jcrs.0000000000001674. PMID: 40241411
- Quantitative Analysis of Choroidal Vascular Remodeling after Cataract Surgery: Correlation with Preoperative Lens Opacity Grading. Mackenbrock LHB, Xu ATL, Łabuz G, Augustin VA, Yildirim TM, Auffarth GU, Khoramnia R. Klin Monbl Augenheilkd. 2025 Aug;242(8):828-835. doi: 10.1055/a-2644-4687. Epub 2025 Aug 21. PMID: 40840458 English.
- International consensuses and guidelines on multifocal intraocular lenses (IOLs) by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO). Rao SK, Safran SG, Gatinel D, Srinivas SP, Miller KM, Leung HYE, Chee SP, Auffarth GU, Chang DF, Dick HB, Eom Y, Lapid-Gortzak R, Grzybowski A, Khanna RC, Lindstrom R, Nanavaty MA, Oshika T, Sharma N, Song JS, Yao K, Yao Y, Yau JCY, Zhang S, Lam DSC, Alió JL. Asia Pac J Ophthalmol (Phila). 2025 Dec 17:100274. doi: 10.1016/j.apjo.2025.100274. Online ahead of print. PMID: 41419160
- [Diagnostic innovations for the early detection and characterization of keratoconus]. Friedrich M, Son HS, Auffarth GU, Augustin VA. Ophthalmologie. 2026 Jan 4. doi: 10.1007/s00347-025-02361-0. Online ahead of print. PMID: 41484590 Review. German.
- Multicenter European Data of Anatomical Parameters of the Anterior Eye Segment Measured with an Optical Biometer. Niknahad A, Son HS, Auffarth GU, Blöck L, Savini G, Coutinho CP, Fernández J, Łabuz G. J Clin Med. 2025 Nov 19;14(22):8192. doi: 10.3390/jcm14228192. PMID: 41303227 Free PMC article.
- In-vitro Comparison of Trifocal Intraocular Lenses of Different Optical Zone Diameter and Design Across Pupil Sizes. Łabuz G, Niknahad A, Yan W, Son HS, Khoramnia R, Auffarth GU. Klin Monbl Augenheilkd. 2025 Aug;242(8):819-827. doi: 10.1055/a-2648-8929. Epub 2025 Aug 21. PMID: 40840459 English.
- Comparing optical quality and simulated defocus curves: head-to-head analysis of hydrophilic and hydrophobic trifocal intraocular lenses. Łabuz G, Yan W, Khoramnia R, Auffarth GU. J Cataract Refract Surg. 2025 Feb 1;51(2):161-166. doi: 10.1097/j.jcrs.0000000000001577. PMID: 39485924
- Quantifying glare phenomena in patients with different intraocular lenses using a standard and modified clinical straylight meter. Naujokaitis T, Rayamajhi A, Auffarth GU, van den Berg TJTP, Khoramnia R, Łabuz G. J Cataract Refract Surg. 2025 Dec 23. doi: 10.1097/j.jcrs.0000000000001865. Online ahead of print. PMID: 41430590
- Assessment of the Efficacy of Restoring Reading Performance After Refractive Lens Exchange With a Trifocal Intraocular Lens. Naujokaitis T, Auffarth GU, Baur ID, Hassel O, Henningsen N, Reitemeyer E, Chychko L, Łabuz G, Khoramnia R. J Refract Surg. 2025 Aug;41(8):e786-e796. doi: 10.3928/1081597X-20250611-02. Epub 2025 Aug 1. PMID: 40778868
- Visual and refractive outcome, higher order aberrations and complications following intraocular lens exchange in eyes without comorbidities. Henningsen N, Khoramnia R, Auffarth GU, Köppe MK, Łabuz G, Yildirim TM. Sci Rep. 2025 Apr 23;15(1):14202. doi: 10.1038/s41598-025-98931-y. PMID: 40269218 Free PMC article.
- Simulated ocular biometry effects on add-power demand in multifocal intraocular lenses. Son HS, Auffarth GU, Baur I, Khoramnia R, Labuz G. J Cataract Refract Surg. 2026 Jan 1;52(1):81-85. doi: 10.1097/j.jcrs.0000000000001763. PMID: 40804759
- Changes of Aqueous Humor Cytokine and Chemokine Profiles in Femtosecond Laser-Assisted Cataract Surgery in Comparison to Conventional Phacoemulsification. Chychko L, Augustin VA, Son HS, Schickhardt SK, Daniel V, Khoramnia R, Auffarth GU. Ophthalmol Ther. 2025 Nov 18. doi: 10.1007/s40123-025-01272-2. Online ahead of print. PMID: 41252069
- Influence of Graft Unfolding Time During Descemet Membrane Endothelial Keratoplasty on Postoperative Endothelial Cell Loss and Visual Acuity. Blöck L, Son HS, Lind J, Friedrich M, Auffarth GU, Augustin VA. Cornea. 2025 Sep 26. doi: 10.1097/ICO.0000000000004004. Online ahead of print. PMID: 41041945
- Impact of baseline visual acuity, time-in-range and early treatment on functional outcomes in DMO: insights from the IRISS outcomes. Kozak I, Khoramnia R, Taylor SR, Chakravarthy U; ILUVIEN Registry Safety Study (IRISS) Investigators Group. Eye (Lond). 2025 Dec 3. doi: 10.1038/s41433-025-04102-8. Online ahead of print. PMID: 41339482
- Increasing dark adaption times and ERG response in landrace pigs - An intraindividual comparison in 20 animals. Ackermann BC, Skrzypczyk L, Geisweid L, Junker N, Wohlfart S, Uhl P, Auffarth GU, Augustin VA, Hammer M. Exp Eye Res. 2026 Jan;262:110733. doi: 10.1016/j.exer.2025.110733. Epub 2025 Nov 10. PMID: 41224185



2025 - Good News!